 |
 |
Dear FSL team, I am struggling a bit with the statistics for my resting state analyses. I have two groups (each 20 subejcts) and a pre and post measurement. I already ran the ICA and now would like to do the dual regression. In this regression I would like to investigate the main effect of group, condition (pre/post) and the interaction (group differences on the difference between post and pre). Should I do a 2by2 anova with 4 EV's (group1 timepoint 1; group 1 timepoint 2; group 2 timepoint 1; group 2 timepoint 2). And then create the following contrast file main effect group: 1 1 -1 -1 main effect time 1 -1 1 -1 interaction: 1 -1 -1 1 However, I read somewhere that I should subtract both conditions for each individual and then compare the two group on this 'subtracted image'?? Is this correct? Any advice would be greatly appreciated!! Thanks! Best Heidi ================================================ Dr. Heidi Jacobs Postdoc researcher Faculty of Health, Medicine and Life Sciences School for Mental Health and Neurosciences Division Cognitive Neuropsychiatry and Clinical Neurosciences Alzheimer Center Limburg [log in to unmask] www.maastrichtuniversity.nl www.heidijacobs.nl Dr. Tanslaan 12, 6229 ET Maastricht P.O. Box 616, 6200 MD Maastricht, The Netherlands T +31 43 38 84 090 F +31 43 38 84 092 ================================================