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Hi Steve, Thanks - demean the set of disease ages. You mean here disease duration right because I have age information in controls it is only the disease duration which is not there for controls. -----Original Message----- From: FSL - FMRIB's Software Library on behalf of Stephen Smith Sent: Thu 9/20/2012 3:20 PM To: [log in to unmask] Subject: Re: [FSL] VBM analysis regressing out clinical measures a clairification If they want you to just regress the within-group effect of duration, then: - demean the set of disease ages - pad with zeros for the non-disease subjects. Cheers. > Hi All, > > Sorry to post this again and again. We are in the review process on a > manuscript so it will be great help to me if someone could clarify the > following for me. The reviewer has asked us to regress out the effect of > disease duration since I don't have disuration measure for controls how to > do this can I leave those cells in my design matrix empty. I tried using > NAN and 0 both didn't work. > > > Thanks > Venkat > > > > =================================== > > > Please consider the environment before printing this e-mail > > Cleveland Clinic is ranked one of the top hospitals in America by U.S.News > & World Report (2012). > Visit us online at http://www.clevelandclinic.org for a complete listing > of our services, staff and locations. > > > Confidentiality Note: This message is intended for use only by the > individual or entity to which it is addressed and may contain information > that is privileged, confidential, and exempt from disclosure under > applicable law. If the reader of this message is not the intended > recipient or the employee or agent responsible for delivering the message > to the intended recipient, you are hereby notified that any dissemination, > distribution or copying of this communication is strictly prohibited. If > you have received this communication in error, please contact the sender > immediately and destroy the material in its entirety, whether electronic > or hard copy. > > Thank you. > =================================== Please consider the environment before printing this e-mail Cleveland Clinic is ranked one of the top hospitals in America by U.S.News & World Report (2012). Visit us online at http://www.clevelandclinic.org for a complete listing of our services, staff and locations. Confidentiality Note: This message is intended for use only by the individual or entity to which it is addressed and may contain information that is privileged, confidential, and exempt from disclosure under applicable law. If the reader of this message is not the intended recipient or the employee or agent responsible for delivering the message to the intended recipient, you are hereby notified that any dissemination, distribution or copying of this communication is strictly prohibited. If you have received this communication in error, please contact the sender immediately and destroy the material in its entirety, whether electronic or hard copy. Thank you.