Rajan,

This is old news.  Ron Kaplan published a lot about sarcosyl extraction of native mitochondrial carrier proteins from "inclusion bodies" in the late 1990's, but there is an equally robust literature stating that sarcosyl is a denaturant.  It is very much dependent on a protein's characteristics as to whether it is sensitive to sarcosyl or not.  One has to just try the experiment.

Cheers,

Michael


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R. Michael Garavito, Ph.D.
Professor of Biochemistry & Molecular Biology
603 Wilson Rd., Rm. 513   
Michigan State University      
East Lansing, MI 48824-1319
Office:  (517) 355-9724     Lab:  (517) 353-9125
FAX:  (517) 353-9334        Email:  rm[log in to unmask]
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On Sep 20, 2012, at 10:33 AM, rajan kumar wrote:

here by i am sending you a paper it may help you.


regards
rajan
ACTREC

<chaps and triton.pdf>