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Any ideas please ?? I think I must be missing something.... I saw a new patient in clinic yesterday with a very odd series of lipid results 54 yr old Caucasian female( not from Luton, but Harpenden) non smoker, type 2 DM ( HbA1c never high according to GP), BMI 35, minimal alcohol consumption No clinical stigmata of hyperlipidaemia Drug History Metformin Amlodipine Candesartan, Venlafaxine Femoston Inhalers for asthma No other real PMH June 2011 Tg 45.0, Chol 8.4 mmol/L Gp started her on Simvastatin 40mg !! July 2011 Tg 5.2 , Chol 4.1 mmol/L No bloods for 12 months 21/8/12 Tg 29.6, Chol 15.2 HBA1c 51mmol/mol 30/8/12 Tg 93.0, Chol 20.4mmol/L All above samples assayed at another lab using Vitros and GP lab reports say samples were lipaemic She was still on Simvastatin 40mg Gp phoned me on 13th Sept and I told her to stop Statin and give her Ciprofibrate 100mg nocte,( so had been taking it for 1 week) and saw her yesterday Her fasting lipids today on Beckman Tg 4.4, Chol 4.0, HDL 1.84 mmol/L FBC ( and MCV),LFT and U and E normal Patient denies any excessive indulgence in fatty foods. Any ideas why this patient had 3 out of 4 such deranged results...? My colleague suggested we give her a " Pizza and chips challenge"..... Many thanks Regards Danielle Dr Danielle B. Freedman MB BS, FRCPath,EurClinChem Divisional Director Diagnostics, Therapeutics and Outpatients Luton and Dunstable University Hospital NHS FT Luton, LU4 0DZ +441582 497212 ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/