Hello James, to ensure, how did you specify these two models with different results exactly? As far as I know mini-block design means that you have a short block with several trials, and you might want to model the whole block as a single epoch or every trial separately. But you talk of different durations for different trials, which I understand as if you are ondering whether to use a fixed duration or a variable duration. So did you compare 1) an event-related model with a fixed duration of 0 s 2) an epoch-related model with variable length for each of the trials 3) a block-design, which collapses several trials? Best, Gabor