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mricron will allow you to draw ROIs. As Bas mentioned, the borders of some regions can't be delineated based on the structural MRI scan alone. For V1, the preferred method is to do retinotopic mapping. One paper that used macrostructural landmarks is Shimony et al. Diffusion Tensor Imaging Reveals White Matter Reorganization in Early Blind Humans. Cerebral Cortex 2012. Best Regards, Donald McLaren ================= D.G. McLaren, Ph.D. Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School Postdoctoral Research Fellow, GRECC, Bedford VA Website: http://www.martinos.org/~mclaren Office: (773) 406-2464 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email. On Tue, Aug 7, 2012 at 4:22 AM, Ce Mo <[log in to unmask]> wrote: > Dear all, > > I am trying to create Anatomical ROIs (e.g. Primary Visual Cortex V1) based > on each individual's structural scan. Are there any softwares that are > capable of this? Or is it better that I do this manually using some codes? > > Many thanks, > Ce