Hi,

We don't currently have a DSC curve-fitting and area calculation in FSL.
You can calculate the raw sum over all intensities in a time-series (i.e. area) by doing:
   fslmaths inputimage -sub baseline -Tmean -mul `fslval inputimage dim4` outputimage
where baseline is an image with a baseline value in each voxel (you could approximate this with:
fslmaths inputimage -Tmin baseline
if the images are not too noisy) and the outputimage will contain the "area" value in each voxel.
Also note that doesn't include any fitting.
If you have a fitted curve (not the parameters, but a reconstructed time-series) then you can use the same code to get your answer.

All the best,
        Mark

On 19 Aug 2012, at 09:24, Moran Artzi <[log in to unmask]> wrote:

> Dear experts,
>
> I have 4D DSC perfusion (time series) image. I want to calculate the "area under the curve" for each voxel i.e. - the amount of signal change over time .
> Is it possible using one of FSL utilities?
>
> Thanks a lot
> Moran
>