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Dear colleagues,

This is to remind you about the upcoming CNIO Frontiers Meeting on Allosteric Regulation of Cell Signalling in Madrid, on 17-19 September 2012. Further, in light of the economic difficulties many scientists are facing, we are offering subscriptions at reduced cost:

Students and CSIC members: 50 €

Companies: 200 €

Others 100 €

(VAT included)

This meeting will bring together world-leading scientists from different backgrounds (see list of speakers below), in particular structural biology, molecular dynamics and drug discovery. For registration, abstract submission and further information, see: http://www.cnio.es/eventos/index.asp?ev=1

This CNIO Frontier Meeting aims to discuss different aspects of allosteric mechanisms that regulate signalling pathways involved in cancer. The talks will cover i) Introduction to allostery (by Jean Pierre Changeaux, one of the founding fathers of the theory of allostery) ii) the diversity of allosteric mechanisms in cell signalling, iii) protein dynamics in allostery and iv) allosteric drug targeting for therapy.

Organisers:

Francesco Gervasio, CNIO, Madrid, Spain

Daniel Lietha, CNIO, Madrid, Spain

Ermanno Gherardi, MRC Laboratory of Molecular Biology, Cambridge, UK

Giulio Superti-Furga, CeMM, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

Confirmed Speakers:

Jean Pierre Changeux, Collège de France, Institut Pasteur, France

Roger Sunahara, University of Michigan Medical School, USA

Timothy A. Springer, Harvard Medical School, USA

Yvonne Jones, University of Oxford, UK

Tom L. Blundell, University of Cambridge, UK

Alfred Wittinghofer, MPI for Molecular Physiology, Dortmund, Germany

Guillermo Montoya, CNIO, Spain

Susan S Taylor, UCSD, USA

Daniel Leahy, Johns Hopkins University, USA

Gerhard Hummer, NIH Bethesda, USA

Ruth Nussinov, NCI Frederick, USA

Nikolay V. Dokholyan, School of Medicine University of North Carolina, USA

Jose Onuchic, Center for Theoretical Biological Physics at Rice and UCSD, La Jolla, USA

Dorothee Kern, Brandais University, USA

Alfonso Valencia, CNIO, Spain

Michael J. Eck, Dana-Farber Cancer Institute, Harvard Medical School, USA

Markus G. Grütter, University of Zurich, Switzerland

Françoise Bono, SANOFI AVENTIS SA, Toulouse, France

Jeffrey R. Peterson, Fox Chase Cancer Center Philadelphia, USA

Doriano Fabbro, Novartis Pharma AG, Basel, Switzerland

Best regards,
Francesco Gervasio and Daniel Lietha