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Just to wrap up what you may find on the mailing list, the easiest would be to use Christian (Gaser) VBM8 toolbox to read raw volumes. Or alternatively use this MATLAB script for calculating the volume for each tissue class image and sum all the results, this was originally posted by Donald (McLaren).

All the best,
Arman

 %GM_volume calculation for example
    
    V=spm_vol(gm_file);
    Vols = zeros(numel(V),1);
    
    for j=1:numel(V),
        
        tot = 0;
        
        for i=1:V(1).dim(3),
            
            img = spm_slice_vol(V(j),spm_matrix([0 0 i]),V(j).dim(1:2),0);
            
            img = img(isfinite(img)); % <-- exclude non-finite values
            
            tot = tot + sum(img(:));
            
        end;
        
        voxvol = abs(det(V(j).mat))/100^3; % volume of a voxel, in litres
        
        Vols(j) = tot*voxvol;
        gm_volume=Vols(j);
        
        
    end


________________________________
 From: Marko Wilke <[log in to unmask]>
To: [log in to unmask] 
Sent: Friday, July 27, 2012 7:36 PM
Subject: Re: [SPM] TIV
 
Dear Rosalia,

for newcomers in particular, the archives of this very mailing list offer a wealth of information that can be used to answer most, if not all, of your basic questions. For example, a search for "total intracranial volume" gets you more than 50 hits. Those not answered after searching the archives at https://www.jiscmail.ac.uk/cgi-bin/webadmin?S1=spm are particularly welcome on the list :)

Cheers,
Marko

Rosalia Dacosta wrote:
> Dear SPM experts,
> Sorry for this basic question.
> I am new with SPM and I would like to calculate Total Intracranial Volume...
> Any one of you could kindly tell me how can I do it?
> Best regards,
> 
> Rosalia.

-- ____________________________________________________
PD Dr. med. Marko Wilke
Facharzt für Kinder- und Jugendmedizin
Leiter, Experimentelle Pädiatrische Neurobildgebung
Universitäts-Kinderklinik
Abt. III (Neuropädiatrie)


Marko Wilke, MD, PhD
Pediatrician
Head, Experimental Pediatric Neuroimaging
University Children's Hospital
Dept. III (Pediatric Neurology)


Hoppe-Seyler-Str. 1
D - 72076 Tübingen, Germany
Tel. +49 7071 29-83416
Fax  +49 7071 29-5473
[log in to unmask]

http://www.medizin.uni-tuebingen.de/kinder/epn/
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