We struck the same concerns when
transitioning to an Abbott track system from manual analyser workstations. Staff
did not believe that lipaemic samples were being managed as well as the previous
manual visual identification protocols. Regardless of the known impact of
turbidity and water fraction displacement of the chylomicron fractions when we
reviewed all the results from manual reruns of clarified samples performed by
the staff to those of the results performed on the track under the Abbott
quoted interferences indexes there were no outliers.
The Abbott Index protocol was determined
to be accurate and robust within the limits quoted in the kit inserts and the
assays were able to accommodate a wide range of interferences reliably. There
is now no manual intervention or sample management on the track unless
indicated by the index values. The intervention on samples under the manual
analytical workstations was deemed excessive and wasteful of resource.
Cheers,
JB
John Blennerhassett
Senior Medical Scientist in Charge
Core Laboratory Biochemistry
Core Clinical Pathology and Biochemistry
PathWest
Phone: +61 (0)8
92241173
Fax:
+61 (0)8 92242492
From:
Clinical biochemistry discussion list [mailto:[log in to unmask]]
On Behalf Of Maria Fitzgibbon
Sent: Thursday, 5 July 2012 23:45
To:
[log in to unmask]
Subject: Attn Abbott users
I would be grateful if any Abbott users would be happy
to share the configuration of your lipaemia index with me. Our index differs
significantly in samples with high Tgs for example, Sample 1 had Tg of
39.7mmol/L with a lipaemia index of 9.87, Sample 2 with Tg of 36.73mmol/L had
an index of 4.83. We set the lip index at 5 for certain chemistries and ISEs
but I am concerned that since we went to a tracked system, we are now not
detecting samples that would previously have had further centrifugation and direct
ISE measurement.
Many thanks, Maria
Dr Maria Fitzgibbon, FRCPath,
Consultant Clinical Biochemist,
Head of Department of Clinical Biochemistry &
Diagnostic Endocrinology,
Tel: 0035318032423
email: [log in to unmask]
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