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We struck the same concerns when transitioning to an Abbott track system from manual analyser workstations. Staff did not believe that lipaemic samples were being managed as well as the previous manual visual identification protocols. Regardless of the known impact of turbidity and water fraction displacement of the chylomicron fractions when we reviewed all the results from manual reruns of clarified samples performed by the staff to those of the results performed on the track under the Abbott quoted interferences indexes there were no outliers. The Abbott Index protocol was determined to be accurate and robust within the limits quoted in the kit inserts and the assays were able to accommodate a wide range of interferences reliably. There is now no manual intervention or sample management on the track unless indicated by the index values. The intervention on samples under the manual analytical workstations was deemed excessive and wasteful of resource. Cheers, JB John Blennerhassett Senior Medical Scientist in Charge Core Laboratory Biochemistry Core Clinical Pathology and Biochemistry PathWest Royal Perth Hospital Phone: +61 (0)8 92241173 Fax: +61 (0)8 92242492 Mobile: +61 (0)407771332 email: [log in to unmask] <mailto:[log in to unmask]> ________________________________ From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Maria Fitzgibbon Sent: Thursday, 5 July 2012 23:45 To: [log in to unmask] Subject: Attn Abbott users I would be grateful if any Abbott users would be happy to share the configuration of your lipaemia index with me. Our index differs significantly in samples with high Tgs for example, Sample 1 had Tg of 39.7mmol/L with a lipaemia index of 9.87, Sample 2 with Tg of 36.73mmol/L had an index of 4.83. We set the lip index at 5 for certain chemistries and ISEs but I am concerned that since we went to a tracked system, we are now not detecting samples that would previously have had further centrifugation and direct ISE measurement. Many thanks, Maria Dr Maria Fitzgibbon, FRCPath, Consultant Clinical Biochemist, Head of Department of Clinical Biochemistry & Diagnostic Endocrinology, Mater Misericordiae University Hospital, Eccles St, Dublin 7. Tel: 0035318032423 email: [log in to unmask] ________________________________ This e-mail and any files transmitted with it contain information which may be confidential and which may also be privileged and is intended solely for the use of the individual or entity to which it is addressed. Unless you are the intended recipient you may not copy or use it, or disclose it to anyone else. Any opinions expressed are that of the individual and not necessarily that of Mater Misericordiae University Hospital. ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/