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What's the current advice on assessing acetylator status in this situation? Jonathan On 27 Jul 2012, at 09:30, Louise Ward wrote: > Dear All, > A GP has called to ask if there is a test to check for 'sulphonamide sensitivity'. > A rheumatologist has suggested sulphadiazine for a female patient of his for her RA. In her notes there is a record of previous problems with sulphonamides years ago whilst the patient was in Canada (so no access to the records). > The BNF provides a list of cautions including 'monitor blood counts on prolonged treatment; discontinue immediately if blood disorders or rash develop; predisposition to folate deficiency or hyperkalaemia; elderly; asthma; G6PD deficiency; hepatic impairment; renal impairment' > Apart from exclusion of G6PD deficiency (patient origins unknown) and monitoring the treatment as described above, any other suggestions? > Thank you very much! > Best wishes, Lou > > Louise Ward, Clinical Scientist, Bedford. > ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/