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Dear Baidya, There is beamformer source extraction function in SPM beamforming toolbox. However, it might not be convenient for extracting data from thousands of sources as it was intended for much smaller numbers. That function uses Fieldtrip code and if you use it as an example and read Fieldtrip documentation (http://fieldtrip.fcdonders.nl/) you can modify it in a way that would be more suitable for you. One thing you should understand is that the number of independent sources in MEG data cannot exceed the number of channels and usually is much less than that. So you cannot blindly interpret the signal extracted using beamforming from a particular set of coordinates as the actual physiological activity of the corresponding part of the brain. See the references below for some discussions of that: http://www.ncbi.nlm.nih.gov/pubmed/21319268 http://www.ncbi.nlm.nih.gov/pubmed/12948691 http://www.ncbi.nlm.nih.gov/pubmed/15340934 Finally the MEG group in Oxford is interesting in resting state analysis and they base their code on SPM. So you might be interested in talking to them. I CC this to Mark who can tell you more. Best, Vladimir On Wed, Jun 6, 2012 at 4:20 PM, Baidya Nath Saha <[log in to unmask]> wrote: > Vladimir, > > Sorry to bother you about an analysis question. I would like to analyze > resting state MEG data (5 minutes) from a CTF 275 system. Does the MEG > functionality in SPM8 allow extracting the entire time course in source > space via beam forming (e.g for each of the 5 mm grid voxels that can then > be transformed to MNI space)? Should I be using some other software to get > these time courses? Do you know of any informational resources/scripts > already written for resting state MEG connectivity on the full time course? > > Thanks > Baidya > >