Dear SPM users,
In SPM 8, I used an independent t-test to compare two genotype groups on a task, and I included a categorical covariate (control or patient) in the model. As an alternative, I also tried a full factorial with two factors, diagnosis and genotype. However, these tests give completely different results, and I'm not sure why. I set the full factorial as follows:
Factor 1 (genotype):
Levels - 2
Independence - Yes
Variance - Unequal
Factor 2 (diagnosis):
Levels - 2
Independence - Yes
Variance - Unequal
If anyone has any advice it would be greatly appreciated. I've also included the design matrix for the full factorial model, perhaps there is a problem with it?
Kind regards,
Omar Mothersill
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Omar Mothersill
Room 0.18
Neuropsychiatric Genetics Group
Dept. of Psychiatry
Trinity Centre for Health Sciences
St. James's Hospital
Dublin 8.
Phone: 01 896 2464
Email: [log in to unmask]