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Hi FSL users, I am getting clusters as large as 70,000 voxels after running randomise using the TFCE option. Should I be worried getting such a big cluster linking almost all major tracts of the brain? I am aware of the cluster-based thresholding but am not sure if that will help getting more specific clusters and am also not exactly sure of what threshold (zstat value) I should be putting in. My randomise command is as follow for your reference: randomise -i all_FA_skeletonised -o tbss -m mean_FA_skeleton_mask -d design.mat -t design.con -n 5000 -x --T2 -V Thanks a lot, Bonnie