Dear FSL users and experts,
I compare for a study 2 very highly controlled samples of patients, and I
realized shape analysis on hippocampus between my two groups with the new great tool FIRST.
Our results are very interesting
according to our hypothesis.
Un fortunately, these results don't survive
with the FDR correction for multiple comparisons, that is the one
available for vertex analysis.
I read on fsl-mailing list, that M. Jenkinson explained that FDR
thresholding is "not the most sensitive technique for surface inference".
Thus, I ask myself if correction for multiple comparison is essential for the vertex analysis with FIRST or if it is possible to present uncorrected results for a publication ?
I thank you very much in advance for attention and your answer.
Best regards,
Ali Amad