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Hi - Most of the cortex projects to the corpus callosum, so that is not surprising. If you change the threshold, you will see that the medial cortex has the highest probability (U shaped bundle). Cheers Saad On 14 Jun 2012, at 13:42, SUBSCRIBE FSL Jay wrote: > Hello, > > I am using probtrackx to track the fibers in corpus callosum with default parameter settings. when i draw a single roi in the mid sagittal plane so that it covers the entire corpus callosum, i see that it shows connectivity to almost entire brain (fibers connecting to 3/4th of the entire brain). I would normally expect to see the thick U shaped bundle connecting both the left and right hemispheres. > > How do i interpret these huge number of fibers tracked using PROBTRACKX? > > BW > Jay > -- Saad Jbabdi University of Oxford, FMRIB Centre JR Hospital, Headington, OX3 9DU, UK (+44)1865-222466 (fax 717) www.fmrib.ox.ac.uk/~saad