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Thanks alot for your reply, but actually, there is no old file in the directory and I am pretty sure that the timepoints are correct, so is there a way I could check that again, or may be could be be because of other reasons? thanks again Ladan ________________________________ From: "MCLAREN, Donald" <[log in to unmask]> To: [log in to unmask] Sent: Thursday, May 10, 2012 4:36:59 PM Subject: Re: [SPM] problem with estimation Make sure that: (1) you don't have old files in the directory you are trying to write the file to (e.g. remove old files related to the SPM.mat file - ResMS, mask, beta*, etc.); and (2) that you have data at each timepoint or in each subject. Best Regards, Donald McLaren ================= D.G. McLaren, Ph.D. Postdoctoral Research Fellow, GRECC, Bedford VA Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School Website: http://www.martinos.org/~mclaren Office: (773) 406-2464 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email. On Thu, May 10, 2012 at 3:53 PM, ladan ghazisaidi <[log in to unmask]> wrote: Hello, > > >I use SP8 to analyse my data, At firts level statistical analysis, I have created the SPM.mat files and when I try to estimate them, it stops after a few seconds and gives me a message that reads : No inmask voxels: empty analysis and a more detailed message appears on Matlab: > >Initialising parameters : ...done >Plane 46/46 , block 1/1 : ...done >Failed 'Model estimation' >Reference to non-existent field 'Vbeta'. >In file "C:\Users\LA\Documents\spm8\spm8\config\spm_run_fmri_est.m" (v3691), function "spm_run_fmri_est" at line 100. >The following modules did not run: >Failed: Model estimation > >Could you please tell me what it means and how to correct that? >Your help is very much appreciated, >Ladan > >Ladan ghazi Saidi,BSc, MA, >PhD. Candidate in Biomedical Sciences, >UdeM, CRIUGM > >