Use a two-sample t-test.

Best Regards, Donald McLaren
=================
D.G. McLaren, Ph.D.
Postdoctoral Research Fellow, GRECC, Bedford VA
Research Fellow, Department of Neurology, Massachusetts General Hospital and
Harvard Medical School
Website: http://www.martinos.org/~mclaren
Office: (773) 406-2464
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On Mon, May 7, 2012 at 2:54 PM, Mike Sugarman <[log in to unmask]> wrote:
Hell0 SPM Experts,

This may be a relatively elementary question, but I would appreciate any assistance available. I am working with a library of task-activated PET scans, and I have a contrast of task condition (experimental > control). I also have two groups (patients and controls), and I would like to compare this contrast across groups. I have been successfully able to view the contrast within each group, but am puzzled by how to analyze the between-groups comparison. How would I set up my design and/or contrasts to best observe this?

Many thanks in advance,
-Mike Sugarman