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Hi - in general, no. Cheers, Steve. On 30 Apr 2012, at 08:27, Amy wrote: > Hello, > > I'd like to know if it's okay to use controls that have different scanning parameters to compare with the patient group? For example, patients' resting state bold were collected with a TR of 3s and controls with 2s. > > Thanks, > Amy > --------------------------------------------------------------------------- Stephen M. Smith, Professor of Biomedical Engineering Associate Director, Oxford University FMRIB Centre FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve ---------------------------------------------------------------------------