I'm not sure that there is a good way to do this analysis as your wanting to do a repeated-measures ANCOVA. I would simplify the issue and compute the time1-time4 difference and then correlate that with the F-M difference between time1-time4. Best Regards, Donald McLaren ================= D.G. McLaren, Ph.D. Postdoctoral Research Fellow, GRECC, Bedford VA Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School Website: http://www.martinos.org/~mclaren Office: (773) 406-2464 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email. 2012/3/7 华续赟 <[log in to unmask]> > Dear all: > I have a group of 16 subjects with 4 time point fMRI scans. I > want to do longitudinal analysis to found out what was correlate with the > motor recovery ( F-M scores), Which design in the Factorial design > specification should I choose? Where to input the F-M scores? Thank you for > all of your kindness > Best Regards~ > > -- > > Xu-Yun Hua, M.D. > > Department of Hand Surgery > > Huashan Hospital > > No.12 Middle Wulumuqi Road, 200040,Shanghai, China > > E-mail: [log in to unmask] > > >