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OK I found a message from Steve (https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ind0711&L=FSL&P=R23923&1=FSL&9=A&J=on&d=No+Match%3BMatch%3BMatches&z=4), so the cope images would be better as "statistical interactions with non-orthogonal  
regressors (such as motion confound covariates, if used), will be  taken into account."

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