I perfectly agree: really
great book.
dott. Federico Barbani
Servizio Committenza
Azienda USL di Modena
via San Giovanni del Cantone 23
41100 MODENA
tel 059/435813 - 435731
Da: Evidence based
health (EBH) [mailto:[log in to unmask]] Per conto di Richard Saitz
Inviato: lunedì 5 marzo
2012 16.40
A: [log in to unmask]
Oggetto: Re: lead time error
Coming back to this
discussion late, I have one suggestion of a source to read about this issue:
http://www.amazon.com/Overdiagnosed-Making-People-Pursuit-Health/dp/0807022004
Welch, Schwartz and
Woloshin
Best
rich
From:
Evidence based health (EBH) [mailto:[log in to unmask]] On Behalf Of Amy Price
Sent: Friday, February 24, 2012
12:44 AM
To:
[log in to unmask]
Subject: lead time error
"For some diseases, early detection does not help to prolong
life because earlier treatment is no more effective than later
treatment.In these situations, early detection simply increases the years of
disease from the time of diagnosis rather than increasing years of life.
This is called ‘lead time bias’. "
Who thinks this applies to breast cancer and why
or why not? I have two trees one says that screeening does not change life
expectancy, I originally thought they dont know because it has not been long
enough but screening has been in place since the 80s so 30 years should
be enough....on the other hand researh points to increased life expectancy and
quality of life if the primary tumour is excised in metastic breast
cancer.....so could this mean that unless it is big it doesn't matter the body
will self repair or does it say other forces to increase malignancy have come
into paly and the life of a 50 year old is much different than it was in the
eighties.
I need to say this picture of lead time is almost
too horrible to contemplate and my mind keeps freezing but what if all that is
done made no difference what is the point of screening to make someone miserable?
Does early treatment make a difference and if so how much?
Best
Amy
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