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As a follow up question the bulletin board, why is SEP a peptide (L-peptide) and TPO not (non-polymer)?

 

Joel

 

_________________________________

Joel Tyndall, PhD

Senior Lecturer in Medicinal Chemistry
National School of Pharmacy
University of Otago
PO Box 56 Dunedin 9054
New Zealand  

Skype: jtyndall
http://www.researcherid.com/rid/C-2803-2008

Pukeka Matua
Te Kura Taiwhanga Putaiao
Te Whare Wananga o Otago
Pouaka Poutapeta 56 Otepoti 9054
Aotearoa

Ph / Waea               +64 3 4797293
Fax / Waeawhakaahua     +64 3 4797034

 

From: CCP4 bulletin board [mailto:[log in to unmask]] On Behalf Of Rajesh kumar
Sent: Thursday, 22 March 2012 12:00 p.m.
To: [log in to unmask]
Subject: [ccp4bb] refining phosphorylated residues

 

Dear All,

 

I have a structure of a protein and peptide complex, in which peptide has modified residues ( phosphoserine and phosphothreonine). 

During refinement these both gets disconnected  with adjacent residues and its hard to connect them.

Could you please suggest me some options.

 

Thanks

Rajesh