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A 3.5 years PhD studentship is available from October 2012 in the group led by Dr Alessio Ciulli to design and develop novel small molecule chemical probes that target protein interfaces that recognise post-translational modifications of protein amino acids. This multi-disciplinary project will combine molecular/structural biology and biophysical studies of protein-protein complexes with small molecule drug design and organic synthesis. For a recent example of our approach see Buckley et al. J. Am. Chem. Soc., 2012, 134 (10), pp 4465–4468 (http://pubs.acs.org/doi/abs/10.1021/ja209924v).
Applicants should have (or expect to obtain) at least the equivalent of a UK II.1 honours degree (and preferably a Masters) in chemistry, biochemistry, chemical biology, structural biology or other relevant discipline. Applications from students with either a strong chemical or biological science background are encouraged, where the applicant is interested in learning the other discipline. The studentship will cover tuition fees and a maintenance grant for EU nationals who satisfy the eligibility requirements of the UK Research Councils. Owing to funding restrictions, the studentship is not available to non-EU nationals.
Informal enquiries about the post can be sent to Dr Alessio Ciulli at
Closing Date: 31 March 2012
Information on how to apply: http://www.jobs.cam.ac.uk/job/-14772/
best wishes,
Alessio