Dear Crystallographers,
Can anybody guide me how to reduce R-factor, means which are the basic parameters I have to look for to reduce the R-factor during refinement. I am newly learning the refinement. After running molrep R-factor is around 53% (100% identity), after rigid body refinement its showing around 49% and after restrained refinement its showing around 47%. Highest resolution is 2.5A.
Regards
Dipankar