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The deformations utility should be able to take care of this. You'd set up a job using Utilities->Deformations, which has the following structure. Composition . Inverse . . Composition . . . Imported _sn.mat . . . . Parameter File [Your sn.mat file] . . . . Voxel sizes [NaN NaN NaN] . . . . Bounding box [NaN NaN NaN; NaN NaN NaN] . . Image to base inverse on [Your subject's image] Save as Apply to [Your MNI space mask image] Output destination [up to you] Interpolation Nearest neighbour Best regards, -John On 15 February 2012 22:14, Krisanne Litinas <[log in to unmask]> wrote: > Hello SPM community: > > I apologize if this question has been answered before and I am not seeing > it. > > I am trying to find the best way to warp a functional mask from standard MNI > to subject space. From earlier pre-processing steps I have computed two > "_sn.mat" files -- they contain the affine transformation information for > (1) the subject's fMRI (which has been realigned and coregistered to the > anatomical) --> EPI template and (2) the subject's T1 anatomy --> T1 > template. > > Our processing ultimately produces binary masks (in MNI space) that contain > ones for points of interest and zeros everywhere else. I'd like to be able > to transform this mask back to subject space so that I can overlay the > points of interest for display purposes. > > Is there a good way to do this? Can I somehow just apply the inverse of the > affine matrix calculated in the original "_sn.mat" file used to normalize > fMRI to the EPI template? I am currently using SPM5 so I have not used > DARTEL transformation features in SPM8 thus far, but could > this functionality be of help here? > > Thanks, > -Krisanne