Dear List,
first of all, best wishes for 2012 to the SPM community! Hope it will be
a productive year for you all with lots of new and interesting developments.
I was hoping for some advise. I am now working with high-field
high-resolution images, and am trying to perform coregistration of 2
images of different modality (EPI (DWI B0) to T1). The EPI data also has
a near 1mm cubic resolution. It appeared to me that the default settings
of coreg>estimate dont do a very good job for my data, results are
always up to 2 mm off. Note that deformation of the EPI images is close
to zero as we use very good real-time higher order shimming procedures
during acquisition.
Is it required to change some of the coreg options, for example
'separation', 'tolerance' or 'histogram smoothing'?
I read in the manual that 'separation' refers to "The average distance
between sampled points (in mm). Can be a vector to allow a coarse
registration followed by increasingly fine ones.". The default is [4 2].
When working with EPI and T1 data where EPI is also near 1 mm cubic,
would for example [2 1] work better? It appears so, but I would like to
hear about experiences others have with this. Also with respect of
realignment and normalization of high resolution data.
Thank you all in advance!
Bas
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Dr. S.F.W. Neggers
Division of Brain Research
Rudolf Magnus Institute for Neuroscience
Utrecht University Medical Center
Visiting : Heidelberglaan 100, 3584 CX Utrecht
Room B.01.1.03
Mail : Huispost B01.206, P.O. Box 85500
3508 GA Utrecht, the Netherlands
Tel : +31 (0)88 7559609
Fax : +31 (0)88 7555443
E-mail : [log in to unmask]
Web : http://www.neuromri.nl/people/bas-neggers
: http://www.neuralnavigator.com (CEO)
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