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The segmentation does not work so well for PET data, so I don't think you'll be able to use Dartel to improve the inter-subject alignment. Best regards, -John On 23 January 2012 08:56, Chris Leatherday <[log in to unmask]> wrote: > Dear SPM experts, > > I would like to spatially normalise a batch of functional (FDG-PET) images to MNI space, but I do not have strutural images for any of the subjects. Is it possible to use the segment function and/or use DARTEL for spatial normalisation in this case? > > Thank you > Chris Leatherday > PhD Candidate, Curtin University.