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Dear FSL experts, I am running a TBSS analysis to test the group differences in FA between two groups. As suggested by the TBSS manual, i performed the 2-sample t-test implemented in the randomise program to evaluate the differences in FA between patients and controls, when controlling for age and sex. Does the TBSS still perform the t-test by comparing the mean of residuals of FA between two groups, after controlling for these covariates? In other words, does the controlling part make the stats become ANOVA rather than t-test? Any help and suggestion will be appreciated. Johnny