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Dear All, We do not use gel tubes (BD SSTII or PSTII) for phenytoin or carbamazepine but use them for other drugs typically measured on routine immunoassay platforms. Part of the validation was the attached poster from 2007. For all the special drugs measured by HPLC we use non gel tubes, with lack of evidence of non interference being the major factor. Regards, Graham Graham Jones Staff Specialist in Chemical Pathology St Vincent's Hospital, Sydney Ph: (02) 8382-9160 Fax: (02) 8382-2489 >>> maria warner <[log in to unmask]> 27/01/2012 10:44 pm >>> I have also considered this, and contacted Sarstedt. They sent me the attached poster. Obviously these aren't the same as your tubes but it may help! I have also attached a paper where a group did look at BD tubes. Maria On 26/01/2012, Dr Geoff Smith <[log in to unmask]> wrote: > Dear All, > > > > For some time we have asked requestors to send us plain (non-SST, > non-PST) samples for TDM (phenytoin, carbamazepine, valproate, > theophylline, phenobarbitone and digoxin). This is because of > information published some time ago that suggested that some / all of > these drug assays can be affected by the presence of the gel in the > tubes. Does anyone know if this is still the case for the current > generation of blood collection tubes? We're using plastic BD > Vacutainer. > > > > Thanks > > > > Geoff Smith > > > > > > __________________________________________ > > > > Southern Community Laboratories > > > > 3rd Floor, Clinical Services Building > > Dunedin Hospital > > 201 Great King St > > Dunedin 9016 > > New Zealand > > > > T: +64 3 470 2921 > > M: +64 275 545 262 > > F: +64 3 470 2992 > > ___________________________________________ > > > > > > > ------ACB discussion List Information-------- > This is an open discussion list for the academic and clinical community > working in clinical biochemistry. > Please note, archived messages are public and can be viewed via the > internet. Views expressed are those of the individual and they are > responsible for all message content. > ACB Web Site > http://www.acb.org.uk > Green Laboratories Work > http://www.laboratorymedicine.nhs.uk > List Archives > http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html > List Instructions (How to leave etc.) > http://www.jiscmail.ac.uk/ > ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ********************************************************************** This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom they are addressed. If you have received this email in error please notify the system manager. This footnote also confirms that this email message has been virus scanned and although no viruses were detected by the system, St Vincents & Mater Health Sydney accepts no liability for any consequential damage resulting from email containing any computer viruses. ********************************************************************** ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/