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It is valid, yes - with randomise (unlike with GRF). Cheers. On 23 Dec 2011, at 14:55, Tony Goldstone wrote: > Dear FSLers > Using randomise to compare TBSS FA data between two unpaired groups what is the lowest acceptable t threshold to use in the -c option to then use FWE corrected P corrected comparison? > Is -c 1.5 acceptable? > Using the tfce --T2 option does not produce any significant clusters. > Many thanks and Happy Xmas > > Dr Tony Goldstone > MRC Clinical Sciences Centre, Imperial College London, UK > --------------------------------------------------------------------------- Stephen M. Smith, Professor of Biomedical Engineering Associate Director, Oxford University FMRIB Centre FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve ---------------------------------------------------------------------------