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Hi - yes, you can do that - see the MELODIC manual in the FSL documentation, and also the FSL course material and praticals. Cheers. On 19 Dec 2011, at 00:36, Joyce Chen wrote: > Dear FSL, > > I have used csf, wm, physio and motion regressors but my resting state fmri data still look a bit noisy for a few of my subjects. Is it possible to use Melodic (and fsl_reg) to 'further' clean up my data, that is, from data that is already csf/wm/physio and motion corrected. This way, I can avoid having to figure out/pick out these components. If possible, what would the input file be. > > Alternatively, is there some way to include the above regressors in Melodic? Otherwise, my default plan would be to input the raw 4Ddata file, use fsl_reg, and then input the denoised data in Feat, along with the said regressors. Your thoughts? > > Thanks very much! > > Joyce > > > --------------------------------------------------------------------------- Stephen M. Smith, Professor of Biomedical Engineering Associate Director, Oxford University FMRIB Centre FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve ---------------------------------------------------------------------------