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Klim,
It was your initial response that kept me thinking and returned me to the land of reason. I wonder if it would be worth using markers and tracking the cells overtime with a segment of the population. Klim what would you envision as strategies to solving this complexity?
Andy, I really appreciate both the breast and prostate decision aids, these are the best I have seen...great work I like how you have explained the risk factors and the graph is outstanding without being overwhelming.
Paul, these papers are excellent and I learned a lot from reading them that I hope to apply later!
Jo, The lawyers information site was surprisingly informative maybe it is time to merge all for a blog article
Thanks to all for your help and understanding, You are awesome
Best,
Amy
From: Evidence based health (EBH) [mailto:[log in to unmask]] On Behalf Of Klim McPherson
Sent: 21 December 2011 06:02 AM
To: [log in to unmask]
Subject: Re: Breast tumours
Amy,
The whole current controversy surrounding mammography centres on the issue of overdiagnosis. Does it exist if so how common is it? Without doubt removing tumours is much better than not and the earlier the clinical stage the better the survival experience – again without doubt. The evidence is overwhelming. But the question is are there some tumours for which treatment is unnecessary – to which the answer is probably yes, and there may be many. But deciding which is not anywhere near reliable enough right now. Hence the controversy. In my view the guidelines are woefully inadequate and I think women are not given anything like enough information to take proper decisions on an impossible question. That however is no excuse in my view.
Klim
Klim McPherson MA Phd FFPH FMedSci
Visiting Professor of Public Health Epidemiology
Nuffield Dept Obstetrics & Gynaecology
Emeritus Fellow of New College
University of Oxford
Mobile 07711335993
From: "Dr. Amy Price" <[log in to unmask]>
Reply-To: "Dr. Amy Price" <[log in to unmask]>
Date: Wed, 21 Dec 2011 00:39:20 +0000
To: "[log in to unmask]" <[log in to unmask]>
Subject: Breast tumours
Dear all,
Does anyone know how to find out if people who have breast cancers removed have a higher longer survival rate than those who do not? The question was raised that perhaps those with lesions and successful surgery could have perhaps left them in there with no ill results? The thinking was that if it is cancer within a set number of years they will die anyway with or without intervention.
I was too emotionally invested to look at this clearly initially however wilful ignorance does not solve problems but can be a source of alienation. What evidence is there that screening and consequent treatment is not helpful? I do understand that mass screening may be a waste of resources in terms of numbers needed to treat but it seems that the suggested guidelines seem to be evidence starved as well.
Many thanks if someone could direct me to helpful links in this area.
Best,
Amy
Amy Price PhD
Building Brain Potential