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No this is not wrong, both SPM and MRicron are right. The diagonol is 
NOT necessarily equal to the voxel size (it only is for an image without 
any angulation). This matrix is a so called 4D affine transormation 
matrix, constituting the voxel-to-world matrix in the Nifti 
specification from NIH. Don't try to interpret it when you do not know 
what is represents, 4D linear algebra is not for the faint at heart ;-). 
See http://nifti.nimh.nih.gov/nifti-1 for more information on the nii 
specs.

When applying a rotation matrix to the original matrix, the diagonal 
changes, and this is correct behavior (check your linear algebra 
textbooks). When you open your image in spm, the right window will 
compute and display the voxel size for you. This does not change after 
realignment.

When you want to compute it yourself do:

V=spm_vol(spm_select);
inv(V.mat)\[1 1 1 1]'

Good luck,

Bas


Op 25-11-11 10:56, han zhang schreef:
> Hi Helen,
> This problem is also bothering me. The voxel size as indicated in the 
> diagnal of the MAT matrix was sometimes not in concordance with 
> MRIcron (as seen from image 'information' on the menu of MRIcron).
> For example, my MAT matrix of a head-motion-corrected nifti image is :
> -3.4124    0           -0.72       223
> -0.033      3.4263   0.4806   -159
> -0.42        -0.27     5.94      14.7
> The voxel size should be 3.4124* 3.4263*5.94?
> However, MRIcron reported it as 3.5*3.5*7, quite different Huh?
> What I thought is that, maybe after realignment (motion correction 
> with rigid body transformation), the MAT file had been changed, not as 
> diagnal as it should be before. So the voxel size should not be taken 
> from the diagnal number of the MAT file. Am I right?
> Han
>
> 2011/11/25 Helen Beaumont <[log in to unmask] 
> <mailto:[log in to unmask]>>
>
>     Help please.
>
>     I am writing a Matlab matrix (read from a Phillips ParRec file)
>      out as nii data.
>
>     The voxel size is 3.5 x 3.5 x 5.95 mm, 64 x 64 x 20 matrix.
>
>     N.mat is
>
>         3.5000         0         0 -113.7500
>
>              0    3.5000         0 -113.7500
>
>              0         0    5.9500  -62.4750
>
>              0         0         0    1.0000
>
>     When I use SPM to display it, the voxel size is OK, and origin is
>     close to AC.
>
>     However, if I use MRIcroN with “re-orient on load” box checked in
>     preferences,
>
>     voxel size is 1 x 1 x 1 mm, and origin is bottom L corner.
>
>     Helen Beaumont
>
>     ISBE
>
>     University of Manchester
>
>     Stopford Building, Oxford Rd
>
>     Manchester M13 9PT
>
>     Tel: 0161 275 1259
>
>
>
>
> -- 
> Han ZHANG
> http://publicationslist.org/han_zhang
> Center for Cognition and Brain Disorder, Hangzhou Normal University
> Addr: 7th Bldg, Affil Hosp of Hangzhou Normal Univ, Wenzhou Rd 126#, 
> Hangzhou 310015
> Fax/Tel: +86-0571-88285651
> Mobile Tel: 15869174768
>


-- 
--------------------------------------------------
Dr. S.F.W. Neggers
Division of Brain Research
Rudolf Magnus Institute for Neuroscience
Utrecht University Medical Center

Visiting : Heidelberglaan 100, 3584 CX Utrecht
            Room B.01.1.03
Mail     : Huispost B01.206, P.O. Box 85500
            3508 GA Utrecht, the Netherlands
Tel      : +31 (0)88 7559609
Fax      : +31 (0)88 7555443
E-mail   : [log in to unmask]
Web      : http://www.neuromri.nl/people/bas-neggers
          : http://www.neuralnavigator.com (CEO)
--------------------------------------------------


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