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It's a transformation matrix. It converts voxel coordinates to mm coordinates.

http://en.wikipedia.org/wiki/Transformation_matrix

Best Regards, Donald McLaren
=================
D.G. McLaren, Ph.D.
Postdoctoral Research Fellow, GRECC, Bedford VA
Research Fellow, Department of Neurology, Massachusetts General Hospital and
Harvard Medical School
Office: (773) 406-2464
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On Thu, Nov 24, 2011 at 9:25 AM, Glen Lee <[log in to unmask]> wrote:
Dear SPM experts,
 
I'm a novice SPM user and learning by doing.
So, I'm comparing the header information of a bold image (e.g., bold1_0000.nii) before and after realignment.
As can be seen below, the matrix has been changed after realignment for the same given file.
 
 

>> Vol_pre=spm_vol('bold1_0000.nii');
 
>> Vol_pre.mat
ans =
    3.0000         0         0 -123.0000
         0    3.0000         0 -123.0000
         0         0    3.5000  -53.5000
         0         0         0    1.0000
 
 
 

 
>> Vol_post=spm_vol('bold1_0000.nii');
>> Vol_post.mat
ans =
    3.0000    0.0041    0.0054 -123.9010
   -0.0041    3.0000    0.0141 -147.7564
   -0.0046   -0.0121    3.5000  -54.6400
         0         0         0    1.0000
 
 
 
However, I don't know what information this 4 x 4 matrix contain. Any help would be appreciated.
Also, what else in the header information is changed after the realignment?
 
Thanks,
Glen