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Dear SPM users, I have a question concerning second level analysis: I have an experimental design with three conditions, A, B, C, and a baseline. I want to evaluate fMRI activations specifically for each condition versus the two others in my whole group, by testing the contrasts : A-(B+C), B-(A+C) and C-(A+B). So I did for my first level analysis the following three contrasts: A-baseline, B-baseline and C-baseline. At the second level I used a full factorial design with one factor (Condition; three levels: A, B, C) and then I contrasted each condition versus the two others using the following contrasts : 2 -1 -1 ; -1 2 -1; -1 -1 2. Is this approach valid? Do you have any suggestion? Thanks for your help, Marjorie