Hi Nuria, yes it's fine, as long as you have determined which ROI to use *before* obtaining your whole-brain results... Cheers, Gwenaëlle -------------------------------------------------------------------- Gwenaëlle Douaud, PhD FMRIB Centre, University of Oxford John Radcliffe Hospital, Headington OX3 9DU Oxford UK Tel: +44 (0) 1865 222 523 Fax: +44 (0) 1865 222 717 www.fmrib.ox.ac.uk/~douaud -------------------------------------------------------------------- ________________________________ De : Nuria Pujol <[log in to unmask]> À : [log in to unmask] Envoyé le : Vendredi 11 Novembre 2011 12h21 Objet : [FSL] VBM-longitudinal ROI Hello, I performed a longitudinal whole brain VBM analysis using Douaud et al 2009 protocol. In order to test a hypothesis, now I would like to perform a ROI analysis. Would it be correct to perform it using this longitudinal pre-processing for VBM? I did not find any paper about this issue Thanks a lot, Núria