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On 11/08/2011 05:39 AM, james09 pruza wrote: > Dear ccp4bbers, > > I wonder if someone can help me defining proper weight matrix term in > Refmac5 to lower the R-FreeR gap. The log file indicates weight matrix of > 1.98 with a gap of 7. Thanks for suggestions in advance. > James > What is your resolution? The gap is usually wider at lower resolution. Eleanor