Dear Alexander, thank you for your answer; but the box is smaller than the TPM. moreover may I use the Dartel's templates as TPM ? Best, Rosangela Dear Rosangela, Sure - just multiply them with your hippocampal mask. Best wishes, Alexander Am 3 nov. 2011 um 23:10 schrieb Rosangela Errico: > Dear SPM users, > > I have a very basic question, > is It possible use the tissue probability maps, > which are needed for segment, on a hippocampal box? > > Thank you all in advance!