Hi - easiest to use the Glm (or Glm_gui) GUI then, as that will create the design files for you. Cheers. On 12 Oct 2011, at 16:44, Roderick McColl wrote: > I would like to conduct an omnibus F-test on some DTI data with randomise. > > I have four groups with a nuisance EV for age so I have a design.mat which is > > //------------------------------------------- > 1 0 0 0 -10.3 > 1 0 0 0 2.0 > . > . > 0 1 0 0 2.3 > 0 1 0 0 -0.5 > . > . > 0 0 1 0 3.0 > 0 0 1 0 -2.0 > . > . > 0 0 0 1 5.4 > 0 0 0 1 -2.0 > .. > //------------------------------------------ > > and a design.con matrix which is > > 1 0 0 0 0 > 0 1 0 0 0 > 0 0 1 0 0 > 0 0 0 1 0 > > I presume these are correct for obtaining an omnibus F-test. > > However I don't know how to format the design.fts and I can't find and docs on it. > > As a guess is this right ? > > 1 1 1 1 0 > > Thanks > > -roddy > > > UT Southwestern Medical Center > The future of medicine, today. --------------------------------------------------------------------------- Stephen M. Smith, Professor of Biomedical Engineering Associate Director, Oxford University FMRIB Centre FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve ---------------------------------------------------------------------------