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Dear users, Can the optimization of the X-ray weighing factor and B-factor (overall wt) as mentioned in the paper Acta Cryst. (2007). D63, 1274–1281 by Dr.Ian Tickel, be used for the refinement of the data sets beyond the resolution range mentioned in the paper: 1.33 - 2.55 Ang? Also the structures that were used to optimize these parameters were already solved and refined, so when we are solving a new structure to what extent does the model has to be built before starting the optimization? Thanking you With Regards M. Kavyashree -- This message has been scanned for viruses and dangerous content by MailScanner, and is believed to be clean.