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Hi, You can check these pages for information about background and implementation of the conjunction analysis: http://www2.warwick.ac.uk/fac/sci/statistics/staff/academic-research/nichols/research/conjunctions http://www2.warwick.ac.uk/fac/sci/statistics/staff/academic-research/nichols/scripts/fsl/easythresh_conj.sh You also could look into this post: https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=FSL;e2754da.1105 good luck, wolf > Hello, > > We have an interaction effect showing a cluster that shows increased activation (relative to baseline( > in condition A, and reduced activation (relative to baseline) in condition B. > > Referees are asking that we should provide evidence that the differences from baseline is significant in both > condition A and B > > and that we should do this via a Conjunction analysis...would you please help > > 1) we guess this can be done at the highest level? or should we do it at the individual level first? > > 2) we feel that can be done via the contrast masking but we are unsure how to implement the conjunction analyses > > Thanks, David