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Hi - yes you can use fslmaths to achieve the demeaning.  However I'm not sure what you mean by "doing the autocorrelation"; indeed, I would not have thought that DCM would want you to mess with that before feeding the data into it?

Cheers.



On 24 Aug 2011, at 21:55, Hongyu Yang wrote:

Hello list,

We have a question on preprocessing fMRI data. We plan to do DCM analysis in SPM, and need to do preprocess before that. From FSL forum, we learned we can use filtered_func_data or res4d in stats folder, which has been temporally high-pass filtered, motion corrected, nuisance regressor removed. However, we still need to demean the data and finish autocorrelation. From some previous list, it seems we can use fslmaths -Tmean to do demean and film_gls to do autocorrelation, right? Can you give us more details about the commands? I need some positive response to confirm the last two steps for my preprocess.

Thanks,
Hongyu Yang, PhD
Research Specialist in Health Science
Pediatric Brain Research And InterventioN Center
Department of Psychiatry
1747 West Roosevelt Road, M/C 747
Chicago, Illinois 60608
Phone: (312) 413-4622
Fax: (312) 413-0063
Email: [log in to unmask]
http://www.psych.uic.edu/brain-center



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Stephen M. Smith, Professor of Biomedical Engineering
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