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Dear SPMers and experts, I am running a fMRI analysis with 4 conditions and 3 groups (g1=22,g2=17,g3=25). I am using a flexible factorial design with main effect of subject and interaction of groupXcondition. Along with the canonical contrasts, I now need to create a F contrast that reveals voxel showing some form of response that can be induced by the conditions, like the one that would be specified by using eye(12) in a full factorial design with the same conditions and groups. Is there a way to build this contrast in a flexible factorial design? Any help would be appreciated! Stefania