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Dear Mark,
I will try that and contact you if I have any incovinient.
Thank you very much
All the best,
Sabrina

> Date: Thu, 21 Jul 2011 18:30:40 +0100
> From: [log in to unmask]
> Subject: Re: [FSL] design matrix for vertex analysis
> To: [log in to unmask]
> 
> Dear Sabrina,
> 
> You cannot use only two subjects - the statistics will not work.
> Please use at least 3 per group, but ideally all of them.
> 
> All the best,
> 	Mark
> 
> On 21 Jul 2011, at 18:28, diagnostico imagenes wrote:
> 
> > Dear Mark,
> > As I had problems with the vertex analysis (different errors) now I am trying with only two subjects to see if it works. My research sample is 10 patients and 8 controls. Can I try with two subjects or I should do it with the whole sample??
> > 
> > 
> > > Date: Wed, 20 Jul 2011 23:17:29 +0100
> > > From: [log in to unmask]
> > > Subject: Re: [FSL] design matrix for vertex analysis
> > > To: [log in to unmask]
> > > 
> > > Dear Sabrina,
> > > 
> > > Are you really trying to do a vertex analysis between two subjects?
> > > This is really not possible and I would not trust any output that you got.
> > > 
> > > If you meant something else then please let us know.
> > > You should be able to include the design matrix in the email if you
> > > just copy it as text into the email itself.
> > > 
> > > All the best,
> > > Mark
> > > 
> > > 
> > > 
> > > On 20 Jul 2011, at 20:42, diagnostico imagenes wrote:
> > > 
> > > > Dear Mark,
> > > > Now I am using only two subjects to try the vertex analisys and I want to now if there is a difference in the left hippocampus.
> > > > I checked the vtk files in the 3D viewer and it looks fine.
> > > > I tried to attach the design matrix and the vtk files from two left hippocampus but the files are too heavy, how can I send you those files?
> > > > Thank you in advance,
> > > > Best regards,
> > > > Sabrina
> > > > 
> > > > 
> > > > > Date: Tue, 14 Jun 2011 19:33:48 +0100
> > > > > From: [log in to unmask]
> > > > > Subject: Re: [FSL] design matrix for vertex analysis
> > > > > To: [log in to unmask]
> > > > > 
> > > > > Dear Sabrina,
> > > > > 
> > > > > By original analyses I mean the individual subject segmentations.
> > > > > Have you checked these, and do they look correct?
> > > > > 
> > > > > I suspect that the error you see here has something to do with
> > > > > your design matrix. Can you show me the contents of the 
> > > > > file con0_dis1.mat ? Also, let me know how many subjects
> > > > > you have and what sort of question(s) you are trying to ask
> > > > > with this design matrix.
> > > > > 
> > > > > All the best,
> > > > > Mark
> > > > > 
> > > > > 
> > > > > On 14 Jun 2011, at 19:20, diagnostico imagenes wrote:
> > > > > 
> > > > > > Dear Mark,
> > > > > > 
> > > > > > We use the command:
> > > > > > first_utils --vertexAnalysis --usebvars -i con_to_dis_L_Hipp.bvars -d con0_dis1.mat -o shape_analysis/con0_dis1_L_Hipp --useReconNative --useRigidAlign -v >& shape_analysis/con0_dis1_L_Hipp_output.txt
> > > > > > 
> > > > > > It only creates de .txt file inside the shape_analysis folder. An it says "abortado"
> > > > > > and the text in the .txt is
> > > > > > 
> > > > > > read model
> > > > > > done reading model
> > > > > > setting up shape/appearance model
> > > > > > The shape has 732 vertices.
> > > > > > 336 modes of variation are retained.
> > > > > > The model was constructed from 336 training subjects.
> > > > > > model loaded
> > > > > > read model
> > > > > > done reading model
> > > > > > setting up shape/appearance model
> > > > > > The shape has 732 vertices.
> > > > > > 336 modes of variation are retained.
> > > > > > The model was constructed from 336 training subjects.
> > > > > > 1.12962 0.0220672 0.03358 -4.52313 
> > > > > > -0.0133035 1.08221 -0.0541649 8.58251 
> > > > > > -0.0318979 0.0605173 1.15819 -16.5332 
> > > > > > 0 0 0 1 
> > > > > > 1.12962 0.0220672 0.03358 -4.52313 
> > > > > > -0.0133035 1.08221 -0.0541649 8.58251 
> > > > > > -0.0318979 0.0605173 1.15819 -16.5332 
> > > > > > 0 0 0 1 
> > > > > > done recon
> > > > > > done recon and reg
> > > > > > new design matrix
> > > > > > 1 0.5 -0.5 
> > > > > > 1 -0.5 0.5 
> > > > > > evs 1
> > > > > > set hsape Mesh
> > > > > > 1 0 0 
> > > > > > 0 0 1 
> > > > > > do mvglm
> > > > > > terminate called after throwing an instance of 'NEWMAT::SingularException'
> > > > > > 
> > > > > > What do you mean by original analyses?
> > > > > > 
> > > > > > Thank you in advance,
> > > > > > Best regards,
> > > > > > Sabrina
> > > > > > 
> > > > > > > Date: Mon, 6 Jun 2011 21:49:45 +0100
> > > > > > > From: [log in to unmask]
> > > > > > > Subject: Re: [FSL] design matrix for vertex analysis
> > > > > > > To: [log in to unmask]
> > > > > > > 
> > > > > > > Hi,
> > > > > > > 
> > > > > > > Can you please send us the exact commands you tried to run
> > > > > > > and the exact error messages they gave.
> > > > > > > 
> > > > > > > Also, have you checked that all the original analyses were correct?
> > > > > > > 
> > > > > > > If it creates a log directory, please also look at the contents of
> > > > > > > files there too and let us know of any errors.
> > > > > > > 
> > > > > > > All the best,
> > > > > > > Mark
> > > > > > > 
> > > > > > > 
> > > > > > > On 6 Jun 2011, at 20:53, diagnostico imagenes wrote:
> > > > > > > 
> > > > > > > > Thanks Mark,
> > > > > > > > I could create the matrix but now I have a new problem.
> > > > > > > > When I wrote the command to do the vertex analysis, it starts to run but the it says "abortado". It only creates the txt file inside the shape_analysis directory.
> > > > > > > > I created the concatenated bvars using: concat_bvars and then I wrote all the filenames I wanted to concatenate (patients and controls).
> > > > > > > > I hope you can help me
> > > > > > > > Thanks a lot
> > > > > > > > Best regards
> > > > > > > > Sabrina
> > > > > > > > 
> > > > > > > > 
> > > > > > > > > Date: Fri, 3 Jun 2011 21:05:19 +0100
> > > > > > > > > From: [log in to unmask]
> > > > > > > > > Subject: Re: [FSL] design matrix for vertex analysis
> > > > > > > > > To: [log in to unmask]
> > > > > > > > > 
> > > > > > > > > Dear Sabrina,
> > > > > > > > > 
> > > > > > > > > Open the Glm GUI.
> > > > > > > > > Choose the higher-level design.
> > > > > > > > > Set the number of inputs to the total number of subjects.
> > > > > > > > > Select the Wizard.
> > > > > > > > > Choose two groups, unpaired.
> > > > > > > > > Set the number of subjects in the first group.
> > > > > > > > > Press Process.
> > > > > > > > > Check the image looks OK.
> > > > > > > > > Go back to the original (small) window.
> > > > > > > > > Select Save.
> > > > > > > > > Choose the appropriate directory.
> > > > > > > > > Type in a filename.
> > > > > > > > > 
> > > > > > > > > And that's it.
> > > > > > > > > 
> > > > > > > > > All the best,
> > > > > > > > > Mark
> > > > > > > > > 
> > > > > > > > > 
> > > > > > > > > 
> > > > > > > > > On 3 Jun 2011, at 20:55, diagnostico imagenes wrote:
> > > > > > > > > 
> > > > > > > > > > Hi, 
> > > > > > > > > > I am trying to use the vertex analysis for the hippocampus in FSL-FIRST but I am having problems to generate de design matrix. The manual says that I should use the glm in the FSL program with 1 EV and the matrix should be 0 for one group and 1 for the other. I tried to create the matrix by changing the number of inputs but then I canīt save it.
> > > > > > > > > > Can you please give me more detailed instructions to create the matrix??? 
> > > > > > > > > > Thank you very much in advance,
> > > > > > > > > > Best regards,
> > > > > > > > > > Sabrina