On Tue, Jul 12, 2011 at 6:08 PM, Jiamu Du <span dir="ltr">&lt;<a href="mailto:[log in to unmask]"><a href="/cgi-bin/wa-jisc.exe?LOGON=A3%3Dind1107%26L%3DCCP4BB%26E%3Dquoted-printable%26P%3D8059607%26B%3D--bcaec54ee8da50808904a7e924fe%26T%3Dtext%252Fhtml%3B%2520charset%3DISO-8859-1%26pending%3D" target="_parent" >[log in to unmask]</a></a>&gt;</span> wrote:<br><div class="gmail_quote"><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex;">
I am now working on a low resolution phase determination (around 3.3 A with Se anomalous signal around 3.8 A). <br>I can find the Se site and get the phase, but the density map is not so good. <br>Some part of the protein (about 1/3) has a homologue model which is also can be found using Phaser. The homologue region has a good map while other region only show a poor map. <br>

I think the combination of experimental phase and MR phase might improve the map. Is there anybody can help find which program can work on this?<br></blockquote><div><br></div><div>Phaser has been able to do this for years - you need to run it in experimental phasing mode, but include the MR solution as a partial model.</div>
<div><br></div><div>-Nat</div></div>