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Important: Do *NOT* reply to this e-mail to apply for this position. Only applications processed through the apply link will be accepted. Any direct replies to this e-mail will be ignored. Passionate About Science We're passionate and rigorous about our science. For more than 30 years, Genentech has been at the forefront of the biotechnology industry, using innovative science to develop breakthrough medicines that improve the lives of people with serious or life-threatening diseases. The following opportunity exists in our South San Francisco, CA, headquarters: Senior Scientist- X-Ray Crystallography & Technology Responsibilities: Genentech has an opportunity for an outstanding X-ray crystallographer to join the Genentech Structural Biology Department as a Senior Scientist (Technology). The department encompasses protein expression, purification, crystallography, and NMR spectroscopy, and collaborates with scientists and project teams throughout the Research organization. Primary job responsibilities include being an integral member of project teams, creatively applying crystallography to structure-based drug design, and providing strategic and managerial oversight of protein expression, purification and crystallography approaches for projects at all stages of the drug discovery pipeline. In addition to participation on project teams, the successful candidate will be expected carry out innovative research resulting in co- and lead-authored publications on structures of therapeutic and biological importance. Requirements: This position requires a PhD in Structural Biology, Biophysics, Biochemistry or related discipline, relevant post doctoral experience and at least five years of additional experience as an independent scientific investigator or group leader. The candidate must have experience with successfully managing external resource and/or leading multi-disciplinary project teams and a strong publication record in top tier journals is required. Technical expertise in solving X-ray crystal structures including hand-on operation of relevant data collection devices and software packages is required along with an established track record as an effective manager. The ideal candidate is a skillful speaker at high profile internal and external forums. The successful candidate will show evidence of sustained productivity, creativity and independent contributions to science; and must also be highly organized, motivated, work independently in a collaborative team-oriented setting, and have strong managerial and communication skills. The applicant must be passionate about applying structural biology to the pursuit of drug discovery including using structure-based drug design and carrying out cutting edge research on protein complexes of importance to human diseases. Demonstrated scientific leadership resulting in significant achievements either in a collaborative academic setting or in the context of multi-disciplinary projects team in a biotech/pharmaceutical setting is a must. Passionate About Our People We recognize that our people are our most important asset. It's why we foster an inclusive environment that encourages diversity and offer competitive healthcare and benefits to help you bring the best to the business and to your personal life. Join us as we continue to tackle medicine's most challenging problems and live a life inspired. To apply for this job, visit https://roche.taleo.net/careersection/test/jobapply.ftl?lang=en&job=0037 7162&src=JB-11480. Now a member of the Roche Group, Genentech has multiple medicines on the market for cancer and other serious illnesses. We are an equal opportunity employer.