 |
 |
Dear Bob Thanks for raising this. We looked at this within Pathology Harmony phase 2 and chose the pragmatic route of mass units (ng/L not pg/ml) since the vast majority of labs were using this unit, and given the developing nature of the test we felt that trying to orchestrate a change to the (more scientifically appropriate) molar unit would cause further confusion with relation to cut-offs and the like. It would be nice if labs were required to report in molar units wherever possible for novel assays from the outset, but I'm afraid there is a transatlantic influence to contend with... Best regards Gethin By the way we also consulted Paul! Gethin Roberts Cons Clinical Biochemist 01970 63(5784) WHTN 0-1822 5784 -----Original Message----- From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Robert Cramb Sent: 25 July 2011 14:22 To: [log in to unmask] Subject: NT-pro BNP & BNP units No doubt many of us are now offering BNP as part of our repertoire to review heart failure but I wonder if you can help review consensus. The NICE guideline on heart failure (CG108) reviews the evidence in "pg/mL (pmol/L)". When we (at UHB) originally introduced NT-pro BNP for our cardiac transplant unit we adopted pmol/L (SI units; molar function etc.) but now that we are funded to provide GP NT-proBNP tests there is an insistence that we must use pg/mL for all reporting as "that is what is reported by NICE". So CG108 quotes pg/mL and pmol/L but what should we use? I would be grateful of any views from the list members and shall give feedback in a few days. And before you ask him, I did consult Paul Collinson before embarking on this question. Many thanks Bob Cramb ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/