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Hi thanks for the reply. To be a little more specific with my question in regards to conditon A (post-pre) vs condition B (post-pre).

If I follow the standard paired t-test design, it would look like this for condition A's post-pre setup, but how do I compare, for example condition A (post-pre) - condition B (post-pre)?: 
                                                           EV1   EV2 - EV7 (one EV for each subject) 
Input 1 (subject 1, condition A, pre)         1       
Input 2 (subject 2, condition A, pre)         1      
Input 3 (subject 3, condition A, pre)         1       
Input 4 (subject 4, condition A, pre)         1      
Input 5 (subject 5, condition A, pre)         1      
Input 6 (subject 6, condition A, pre)         1      
Input 7 (subject 1, condition A, post)      -1       
Input 8 (subject 2, condition A, post)      -1       
Input 9 (subject 3, condition A, post)      -1       
Input 10 (subject 4, condition A, post)    -1       
Input 11 (subject 5, condition A, post)    -1       
Input 12 (subject 6, condition A, post)    -1       


I hope this makes sense...

Thanks

On Wed, Jun 1, 2011 at 1:14 AM, Stephen Smith <[log in to unmask]> wrote:
Hi - see the FEAT and randomise manuals - this is a standard paired t-test design that you can setup with the Glm GUI and then use that saved design when running randomise.
Steve.


On 31 May 2011, at 21:48, Amy wrote:

Hi all,

I have 6 subjects scanned twice under 2 different conditions. Within each condition (each scan), subjects underwent a pre-intervention and a post-intervention resting state fmri. I want to run dual regression comparing the 2 different conditions to see if there are any significant differences. However, I am not sure how to set up the design in the glm. If I want to compare Condition A's  post-pre to Condition B's post-pre, how would I set that up? Using the FEAT, I can run multiple higher level analyses using the COPE images, but with the model-free resting state analysis, I'm not sure I can find an option like that. I'd greatly appreciate it if anyone has any ideas on how I can do this. Thanks!



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Stephen M. Smith, Professor of Biomedical Engineering
Associate Director,  Oxford University FMRIB Centre

FMRIB, JR Hospital, Headington, Oxford  OX3 9DU, UK
+44 (0) 1865 222726  (fax 222717)
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